地址：武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301
电话：18771997407
传真：13212737804
邮箱：sales@amyjet.com
<艾美捷科技代理Separopore品牌全系列产品
Separopore是美国生物技术公司bioWORLD旗下的核心色谱品牌，Separopore专攻多孔琼脂糖微球色谱介质，主打 "高分辨率分离纯化" 技术，覆盖亲和色谱、离子交换、分子筛等应用场景。产品广泛应用于单克隆抗体/重组蛋白纯化、病毒载体（AAV, 慢病毒）捕获，疫苗抗原精制以及核酸/酶工程等领域。
▍Separopore产品线
| 类型 | 应用场景 | 代表产品 |
| 亲和色谱介质 | 抗体/融合蛋白纯化 | Separopore® Protein A/G |
| 金属螯合介质 | 组氨酸标签蛋白捕获 | Separopore® Ni-NTA |
| 离子交换介质 | 核酸/酶纯化 | Q/S SP/CM 系列 |
| 疏水层析介质 | 膜蛋白/病毒纯化 | Phenyl/Octyl 系列 |
| 分子筛介质 | 脱盐/缓冲液置换 | Separopore® SEC Beads |
Separopore的材料特征：
①基质成分：交联 4% 或 6% 琼脂糖（agarose），形成刚性多孔珠状结构
②物理优势：高孔隙率 & 均一粒径（45-165 μm 可选）；耐压性强（可承受 >0.3 MPa 操作压力）；低非特异性吸附
③表面修饰：可定制化偶联 Protein A/G、镍离子、抗体、凝集素 等配体
▍Separopore部分产品列表
| 品名 | 规格 | 货号 |
| AMP Separopore® 4B-CL | 1 g；3 g | 20181079 |
| Anti-DYKDDDDK (FLAG) Red Separopore® 4B Microbeads viewIP™ | 1 mL | 20181114 |
| Goat Anti-Human IgG Separopore® 4B-CL | 5 mL | 20181134 |
| L-Lysine Separopore® 4B-CL | 5 mL；10 mL；25 mL | 20181070 |
| L-Methionine Separopore® 6B-CL | 10 mL；25 mL | 20181160 |
| L-Phenylalanine Separopore® 4B-CL | 5 mL；10 mL；25 mL | 20181071 |
| L-Proline Separopore® 6B-CL | 10 mL；25 mL | 20181161 |
| L-Serine Separopore® 6B-CL | 10 mL；25 mL | 20181162 |
| L-Threonine Separopore® 6B-CL | 10 mL；25 mL | 20181163 |
| L-Valine Separopore® 6B-CL | 10 mL；25 mL | 20181164 |
| Lens culinaris Lectin (LCA/LCH) - Separopore® 4B OnePASS™ Column | 3.25 mL；8 mL | 30330004-1 |
| Lycopersicon esculentum Lectin (LEL/LEA) - Separopore® 4B OnePASS™ Column | 3.25 mL；6 mL | 30330005-1 |
| Maackia amurensis Lectin (MAA/MAL I) - Separopore® 4B OnePASS™ Column | 3 mL | 20120088-1 |
| Maclura pomifera Lectin (MPL/MPA) - Separopore® 4B OnePASS™ Column | 3 mL | 21511124-1 |
| MagneZoom™ (Paramagnetic Beads) Control | 1 mL；2 mL | 20162011-2 |
| Maltose Separopore® 4B (Epoxy-Coupled) | 10 mL；25 mL；50 mL；100 mL | 20181175 |
| Mannose Separopore® 4B-CL (Divinyl Sulfone-Coupled) | 10 mL；25 mL；50 mL；100 mL | 20181019 |
| Mannose Separopore® 4B-CL (Epoxy-Coupled) | 10 mL；25 mL；50 mL；100 mL | 20111005 |
| Melibiose Separopore® 4B (Divinyl Sulfone-Coupled) | 10 mL；25 mL | 20181178 |
| Melibiose Separopore® 4B (Epoxy-Coupled) | 10 mL；25 mL | 20181148-1 |
| N-Acetyl-D-Galactosamine Separopore® 4B-CL | 2 mL；5 mL；10 mL | 20181021 |
| N-Acetyl-D-Glucosamine (GlcNAc) Separopore® 4B-CL | 2 mL；5 mL；10 mL | 20181022 |
| NAADP Separopore® 4B-CL | 2 g | 20181122 |
| NAADP Separopore® 4B-CL (Carboxyl-Linked) | 2 g | 20181123 |
| Nickel Red Separopore® 4B Microbeads viewIP™ | 1 mL | 20181117 |
| Phaseolus vulgaris Lectin (PHA-E) - Separopore® 4B OnePASS™ Column | 3.25 mL；6 mL | 30330023-1 |
| Phaseolus vulgaris Lectin (PHA-E+L) - Separopore® 4B OnePASS™ Column | 3.25 mL；6 mL | 30330027-1 |
| Phaseolus vulgaris Lectin (PHA-L) - Separopore® 4B OnePASS™ Column | 3.25 mL；6 mL | 30330036-1 |
| Pisum sativum Lectin (PSA/PSL) - Separopore® 4B OnePASS™ Column | 3 mL | 21511137-1 |
invivoCrown IV0105替换BioXCell BE0089
invivoCrown IV0109替换BioXCell BE0164
invivoCrown IV0114替换BioXCell BE0213
<艾美捷科技代理Gene Tools品牌
Gene Tools是一家生产和销售Morpholino Anti-sense oligos（反义寡核苷酸)的公司，其产品专门用于基因调控的科学研究和药物开发。Gene Tools公司由多位资深科学家组成，为全球客户提供免费的技术咨询和Morpholino 序列设计服务。 Morpholino作为基因调控研究的最佳工具，已被广泛用于：阻断靶mRNA 翻译 (下调基因）；诱导RNA选择性剪接 (下调或上调基因）；阻断 miRNA；阻断病毒 RNA；阻断 non-coding RNA。
▍Morpholino介绍
Morpholino属于第三代反义寡核苷酸，主要通过阻断蛋白质翻译过程而达到抑制目标基因功能的作用，目前已经广泛用于发育生物学和细胞学实验中，并取得了非常好的实验效果。
Morpholino以吗啉环类似物为基本骨架，这种独特的结构特性使得Morpholino 具有以下几个特点：
● 与其他类型的反义寡核苷酸相比，Morpholino 能更好地抵抗核酸酶的作用；
● Morpholino 与靶序列结合后通过空间位阻效应发挥作用， 不激活RNaseH，不引起目标基因mRNA 的降解 ；
● 针对翻译起始位点区设计的Morpholino 用于抑制蛋白质的翻译，针对 pre-mRNA 剪切位点区设计的Morpholino 可影响mRNA 剪切，得到不 同的转录本，可以方便地用于目标基因结构域的突变研究；
● 与靶序列结合能力强，可以渗入mRNA 的二级结构， 并且特异性好。
配合Morpholino 的使用，Gene Tools公司开发了相应的递送系统，可以安全、高效地将Morpholino 输送至胞内，因此，Morpholino 也可以用于遗传学研究和新药靶标的发现以及验证。此外，Morpholino 可以标上荧光基团、亲和标签以及活性反应基团，以供不同的研究需要。
▍Gene Tools公司产品介绍
● Custom Morpholino：可以根据目标基因序列定制设计并合成Morpholino，用于体外细胞实验或某些直接显微注射的模型（如斑马鱼、非洲爪蟾胚胎）。
● Vivo-Morpholino：适用于活体动物模型（小鼠，大鼠，狗，灵长类等），细胞培养，器官培养等。通过特殊的末端修饰，提高了其穿透细胞膜进入组织细胞的能力，使得在成年动物（主要是小鼠、大鼠）中进行系统性基因功能研究成为可能。
● Prepared Control Oligos：根据特定需求合成细胞穿透肽偶联的 Morpholino。适用于活体动物模型（小鼠，大鼠，狗，灵长类等），细胞培养，器官培养等。
| 产品名称 | Short Description | Oligo sequence | SKU |
| Standard Control Oligo | Negative control oligo | CCTCTTACCTCAGTTACAATTTATA | PCO-StandardControl-100 |
| Vivo-Morpholino Standard Control Oligo | Negative Vivo-Morpholino control oligo | CCTCTTACCTCAGTTACAATTTATA | PCO-VivoStandardControl-100 |
| Random Control Oligo 25-N | 25-base random sequence mixture | NNNNNNNNNNNNNNNNNNNNNNNNN | PCO-RandomControl-25N-100 |
| Zebrafish p53 oligo | Danio rerio apoptosis suppression oligo | GCGCCATTGCTTTGCAAGAATTG | PCO-ZebrafishP53-100 |
| Zebrafish Chordin Positive Control Oligo | Danio rerio Chordin positive control oligo | ATCCACAGCAGCCCCTCCATCATCC | PCO-ZebrafishChordin-100-F |
| Clawed Frog Beta Catenin Positive Control Oligo | Xenopus laevis Beta Catenin antisense oligo | TTTCAACCGTTTCCAAAGAACCAGG | PCO-BetaCatenin-100-F |
| Green Fluorescent Protein Positive Control | Translation blocker for GFP target | ACAGCTCCTCGCCCTTGCTCACCAT | PCO-GFPControl-100 |
| Vivo-Morpholino GFP Positive Control | Translation blocker for GFP target (Vivo-Morpholino) | ACAGCTCCTCGCCCTTGCTCACCAT | PCO-VivoGFPControl-100 |
| Fluoresceinated Vivo-Morpholino Std Control | Negative Vivo-Morpholino control oligo with 5'Fluorescein | CCTCTTACCTCAGTTACAATTTATA | PCO-FluorVivoStandardControl-100-F |
● Endo-Porter：为了解决Morpholino在体外培养细胞中摄取效率低的问题，Gene Tools 开发了 Endo-Porter 这种特殊的转染试剂。它通过温和的内吞体逃逸机制帮助Morpholino进入细胞质。
invivoCrown IV0103替换BioXCell BE0075-1
invivoCrown IV0107替换BioXCell BE0273
invivoCrown IV0113替换BioXCell BE0075
Toronto Research Chemical建立于1982年，致力于为生物医药研发人员提供小分子有机物，库存超过57000种，并通过一系列方法保证标准物质的纯度。
Toronto Research Chemicals, TRC, was founded in 1982 by Dr. David Dime to manufacture and supply researchers in the biomedical fields with specialized complex organic small molecules that were not commercially available. In 1983, the company was incorporated in Ontario as Toronto Research Chemicals Inc. It was initially located at the University of Toronto. As the business expanded, larger facilities were required to accommodate the growth.
Today, Toronto Research Chemicals Inc. employs about 150 full time staff, of which approximately 80 are PHD's, operating in a 65,000 square foot facility. TRC, currently manufactures and distributes in excess of 33,000 products to more than 65 countries.
Toronto Research Chemical的产品涵盖：
Activators; Affinity Chromatography; Agonists; Agro-Products; Aldehyde Labeling Reagents; Aldehydes; Amines; Amino Acids & Derivatives; Anti-virals; Antibiotics; Apoptosis; Benzodiazepines; Biotin Derivatives; Boron Derivatives; Carbohydrates; Catalysts; Charged Bifunctional Reagents; Charged Monofunctional Reagents; Chelating Agents & Ligands; Chiral Reagents; Chromatography Media; Cross Linking Reagents; Crosslinker; CyanineDyes; Detergents; Diagnostics; Dihydropyridine; Dopamines; DrugAnalogues; ElectrophoresisMaterials; Environmental; Enzyme Substrates; Ephedrines; Fatty Acids & Derivatives; Fentanyls; Fluorescent Labels &Indicators; Glucuronides; Glutathione S-Transferase Agents; Glycerols; Glycosidase Inhibitors; Heterocycles; Hydantoins; Impurities; Indole Derivatives; Inhibitors; Inositols; Isotope Labelled Compounds; Labeling and Diagnostics Reagents; Lipids; Lysergic Acid and Derivatives; Maleimide Derivatives; Mercaptans/Thiols; Metabolites; Methadones and Analogues; Miscellaneous Compounds; Morphine Based Alkaloids; MTS & Sulfhydryl Active Compounds; Mutagenesis Research Chemicals; Neurochemicals; Neutral Bifunctional Reagents; Neutral Monofunctional Reagents; Nicotine Derivatives; Nitric Oxide Reagents; Non-nucleoside Reverse Transcriptase; Nucleotides; Oligosaccharides; Opium Alkaloids - Natural and Derivatives; Peptides; Pharmaceuticals; Phenethylamines; Phosphorylating and Phosphitylating Agents; Phosphorylcholine Derivatives; Photoaffinity Labels; Polyethyleneglycol Derivatives; Polymers; Protein Kinase Inhibitors and Activators; Pyridyl Disulfides; Retinoids; Selenium Compounds; Sphingosine Derivatives; Spin Labeling Compounds; Steroids; Sulfonyl Chlorides; Tyrosine Kinase Inhibitors; Wittig Reagents.
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艾美捷科技有限公司
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" data-original="http://gbiosciences.51antibodies.com/template/company/xys_lvse/skin/image/lazyLoad.jpg" alt="Toronto Research Chemicals"> Toronto Research Chemicals
invivoCrown IV0100替换BioXCell BE0146
地址：武汉市洪山区光谷大道35号光谷总部国际时代 二期1栋1301
电话：18771997407
传真：15172469628
邮箱：sales@amyjet.com
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