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艾美捷科技代理AxisPharm品牌全系列产品


AxisPharm是一家专业的分析服务提供商,致力于为科学研究界和工业界提供高质量的分析服务。凭借先进的仪器设备和专业的技术团队,AxisPharm在生物分析、化学分析和质量控制领域树立了良好的声誉。AxisPharm公司的产品线包括:PEG 连接子、用于药物递送的脂质、荧光染料、单击化学试剂、聚聚乙二醇,共聚物、可裂解的连接子、抗体和抗体药物偶联物ADC、ADC 有效载荷、细胞生物学试剂、脱氧核糖核酸、修饰语、探针、合成肽、目标特定链接器、硫醇反应性接头、酸反应性连接子、胺反应性连接子、羰基反应性连接子、探针、修饰符。


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▍AxisPharm产品线

● PEG连接子:聚合物聚乙二醇是多分散聚乙二醇 (PEG) 聚合物,是一种从石油中提取的聚醚化合物,具有从工业制造到医药的许多应用。

● 用于药物递送的脂质:在药物递送系统中起着至关重要的作用,特别是在脂质体、脂质纳米颗粒或脂质胶束等脂质制剂中。脂质提供结构稳定性,增强药物溶解度,实现控释,并促进靶向药物递送。

● 荧光染料:也称为荧光团或荧光探针,是吸收一种波长的光并以更高波长发射的化合物,从而产生可见荧光。它们是生物学研究中的重要工具,用于标记和检测蛋白质、核酸和细胞等生物分子,从而在显微镜、流式细胞术和实时荧光定量 PCR 等应用中实现灵敏和精确的可视化。

● 点击化学试剂:具有高特异性和最少的副产物,简化了复杂的合成过程。因此,它们在分子生物学、材料科学和药物化学中发挥着至关重要的作用。

● 聚合物聚乙二醇:多分散聚乙二醇 (PEG) 聚合物,是一种从石油中提取的聚醚化合物,具有从工业制造到医药的许多应用。

● 可裂解连接子:一类重要的分子,广泛应用于药物发现、化学生物学和材料科学等各个领域。这些连接子充当两个或多个分子实体之间的连接桥,可以在特定条件下选择性地裂解,从而释放附着的分子。这一特性使它们成为生物活性化合物靶向药物递送、成像和控释的有吸引力的工具。

● 抗体及抗体-药物偶联物及细胞生物学试剂:种类丰富可选择。

● ADC有效载荷:作为 ADC 的三个主要成分之一,有效载荷是高活性和有毒的药物分子,通过化学连接子附着在抗体上。有效载荷可以是小分子、蛋白质毒素、生物活性肽、酶,甚至放射性核素。通过适当的接头与适当的载体系统耦合的有效载荷可能会显示出靶向药物递送的特异性和有效性的提高。

● 脱氧核糖核酸:DNA 是脱氧核糖核酸的缩写,是一种包含所有生物体发育和功能的遗传指令的分子。DNA 由四个基本组成部分组成,称为核苷酸,由糖、磷酸基团和含氮碱基组成。

● 改性剂:改变其他分子或材料特性的化合物。在药物研发领域,改性剂在新型药物递送系统和生物医学设备的设计和优化中发挥着至关重要的作用。一种常见的改性剂类型是官能团,它是赋予分子特定化学和物理性质的原子的特定排列。

● 探针:AxisPharm 提供各种靶标特异性探针,例如叶酸 PEG、生物素 PEG、PROTAC PEG、荧光染料探针和图像探针。探针是一类含有官能团的化合物,旨在选择性地与生物分子(如酶、受体和核酸)相互作用。这些官能团包括荧光染料、生物素和亲和标签等,可以检测和定量复杂生物系统中的特定分子。


Different Types of Polyethylene Glycol PEG Linkers in Stock
Acid PEGDiketone PEGNon-PEG linkerPFP ester PEGSugar PEG β-Glucuronide Linker
Aldehyde PEGDNP PEGPEG-t-butyl esterPhosphonate PEGSulfonic acid PEG
Alkyne PEGDBCO PEGPEG-X-PEGPolymer PEGTCO PEG
Amino PEGDSPE PEGPeptide LinkersPropargyl PEGTetrazine PEG
Aminooxy PEGFluorescent PEGLipid PEGPROTAC LinkerHomobifunctional PEG
Azide PEGFmoc PEGM-PEGSilane PEGBromo PEG
BCN-PEGFolate PEGMaleimide PEGSPDP PEGTosylate PEG
Benzyl-PEGThiol PEGMeNH-PEGBranched PEGBis-Sulfone PEG
Biotin PEGHydrazide PEGNHS ester PEGHyNic PEGDOTA Reagent DOTA PEG
Bis-PEG-acidHydroxy PEGBoc-PEGBis-PEG-NHSIodo PEG
Bis-PEG-NHSCleavable Linkers


Lipids for Drug Delivery
Biotinyl Cap PEDodecanyl PEOther LipidPhosphatidylcholinePhosphatidylethanolamine
Biotinyl PEGlutaryl PEPDP PEPhosphoglycerolPtd Thioethanol
Caproylamine PEIonizable LipidPE MCCPhosphoserineSuccinyl PE
Cationic LipidLipid PEGCyanur PEMPB PE
Fluorescent Dye
AF DyesCyanine DyesMB DyesRhodamine DyeRox (carboxy-X-rhodamine) Dye
APDye FluorsDNP PEGJOER6GPeptide Labeling Reagents
Bodipy ProbesFluorescein (FAM)Pyrene ProbesTAMRA DyeClassic Fluorescent Dyes
IR FluorsQuenchersCoumarin 343

Click Chemistry Tools & Reagents
Alkyne PEGBCN-PEGPTAD LinkerTetrazine PEGClick Chemistry Auxiliary Reagents
Azide PEGDBCO PEGTCO PEGMethylcyclopropene Linkers
Polymer PEG
AcrylateBiotinFmocLipoamideSilane
Active esterBocFolateMaleimideStearic acid
AldehydeCarboxylic acidguanlian1010MW 2000TCO
AmineCholesterolHydrazideMW 5000Thiol
AzideDBCOHydroxylPolysarcosine
Cleavable Linkers
-S-S-CleavablePC CleavableDisulfide LinkersDde Cleavable Linkersβ-Glucuronide Linkers
Cleavable Peptidediazo biotin probesDTSSP crosslinkerPhotocleavable Biotin
Antibody and Antibody Drug Conjugate (ADC)
InotuzumabTrastuzumabEnfortumabLabetuzumab govitecanMirvetuximab soravtansine (solution)
VobramitamabDisitamabMirzotamabLoncastuximab tesirineTrastuzumab deruxtecan (solution)
PolatuzumabOzuriftamabBrentuximabTrastuzumab deruxtecanADC Control Human IgG1-Deruxtecan (DAR 8)
GemtuzumabInebilizumabDatopotamabCofetuzumab pelidotinGlembatumumab vedotin
Daratumumab (PBS)DenintuzumabSacituzumab govitecanBelantamab mafodotinTrastuzumab duocarmazine
PraluzatamabNaratuximabTisotumabEnfortumab vedotin-ejfvTrastuzumab emtansine (solution)
LorvotuzumabRolinsatamabTrastuzumab emtansineTelisotuzumab vedotinEnfortumab vedotin-ejfv (solution)
IzeltabartMipasetamabDatopotamab deruxtecanGemtuzumab ozogamicinBrentuximab vedotin (solution)
LupartumabIladatuzumabORM-5029Cantuzumab ravtansineDepatuxizumab mafodotin
CantuzumabBriobaceptIfinatamab deruxtecanTusamitamab ravtansineADC Control Human IgG1-Deruxtecan (DAR 4)
LonigutamabTamrintamabTisotumab vedotinZilovertamab vedotinDepatuxizumab MMAE
MoxetumomabSacituzumabDisitamab vedotinPolatuzumab vedotinADC Control Human IgG1-vcMMAF
AzintuxizumabUpifitamabBelantamabPivekimabSacituzumab govitecan (solution)
LifastuzumabGlembatumumabPatritumab deruxtecanFarletuzumab ecteribulin
Payloads and Linker modified Payloads
ExatecanBelotecan HClSGD-1882Dolastatin 10MC-Val-Cit-PAB-Doxorubicin
SN 38GimatecanMMAFCalicheamicinGly3-Val-Cit-PAB-MMAE
AmrubicinTaltobulinAuristatin EEribulin MesylateSuO-Glu-Val-Cit-PAB-MMAE
Mitomycin CDxdChlorambucilSoblidotin (Auristatin PE)Fmoc-G-amino-CH2O acetyl-Exetecan
Deruxtecan analogLurtotecanPF-06380101Deruxtecan analog 2DM1-MCC-PEG3-Biotin
sulfo-SPDB-DM4Exatecan mesylateAuristatin FPaclitaxelGGFG-amino-CH2O-acetyl Exetecan
RubitecanMC-DM1MMAF-methyl esterMC-MMD10Mal-PEG8-Val-Cit-PAB-MMAE
(4-NH2)-ExatecanIrinotecanDoxorubicin-SMCCSPDB-DM4DBCO-PEG4-Val-Cit-PAB MMAF
TopotecanPNU-159682MMAD10-HydroxycamptothecinTopotecan Hydrochloride
CL2A-SN38DM47-Ethylcamptothecin

Cell Biology Reagents
Neuro-DiO, lipophilic tracerVU (5-Vinyl-uridine)CM-DiI, lipophilic tracerLumiTracker ER GreenER-Tracker Red (BODIPY TR Glibenclamide)
Annexin V-AF 647 conjugateDAPI, blue fluorescent nucleic acid stainPropidium IodideDeep-Red Fluorescent Nissl StainMitoCLox, mitochondrial lipid peroxidation probe
Annexin V-AF 488 conjugateLumiTracker Mito Rhodamine 123LumiTracker Mito Green FMRAPID DiI, lipophilic tracerLaurdan (6-Dodecanoyl-2-dimethylaminonaphthalene)
Annexin V, His TagThiazole OrangeSynaptoProbe® RedLumiTracker ER RedLinear Polyacrylamide for Nucleic Acid Precipitation
DiD, lipophilic tracerRH 237, potentiometric probeSynaptoProbe® GreenRAPID DiO, lipophilic tracerFluo-4 AM, green fluorescent calcium indicator
DiR, lipophilic tracerHoechst 33342, blue fluorescent nucleic acid stainLumiTracker® Mito Red FMDiI, lipophilic tracerYODi-1, green fluorescent nucleic acid stain
DNA
CPG solid supportsDNA StainsModified Triphosphatesphosphoramidite
Probes
Biotin PEGFolate PEGImage ProbesPROTAC Linker
Amine reactive Linkers
Acid PEGAldehyde PEGBromo PEGMaleimide PEGNHS ester PEG


▍AxisPharm提供的服务

● 蛋白质组学服务:提供质谱分析、蛋白质鉴定和定量服务。专注于生物标志物分析,帮助客户在复杂的生物样本中发现和验证潜在的生物标志物。

● 代谢组学服务:利用先进的LC-MS/MS技术进行代谢物分析,提供通路洞察,帮助客户理解代谢途径和生物过程。

● 高级LC-MS/MS服务:用于PK分析和HPLC分离,确保高精度和高效率的研究结果,提供PK/PD研究,支持药物开发和临床前研究。


▍AxisPharm部分产品列表


Cat#NameM.W.Purity
AP15197Exatecan435.45≥98%
AP15072SN 38392.4≥95%
AP15226Amrubicin483.47≥98%
AP15664Mitomycin C334.3≥98%
AP1520310-Hydroxycamptothecin364.35≥95%
AP152047-Ethylcamptothecin376.41≥95%
AP15210Rubitecan393.35≥95%
AP15211(4-NH2)-Exatecan403.43≥95%
AP15206Topotecan421.5≥95%
AP15207Topotecan Hydrochloride425.5≥95%
AP15202Belotecan HCl433.5≥95%
AP15208Gimatecan447.5≥95%
AP15227Taltobulin473.65≥99%
AP15201Dxd493.48≥95%
AP15209Lurtotecan518.56≥95%
AP15196Exatecan mesylate531.55≥98%
AP15200Deruxtecan analog 2579.58≥95%
AP15205Irinotecan586.68≥95%
AP15224PNU-159682641.62≥98.24%
AP15220Soblidotin (Auristatin PE)701.98≥95%
AP15225SGD-1882725.8≥98%
AP15213MMAF732≥95%
AP15216Auristatin E732≥95%
AP15311Chlorambucil304.21≥98
AP15219PF-06380101743.01≥95%
AP15214Auristatin F746≥95%
AP15215MMAF-methyl ester745.99≥98%
AP15187Doxorubicin-SMCC762.8≥98%
AP15217MMAD771.06≥98%




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艾美捷科技代理Bio Academia品牌。

Bio Academia公司致力于生命科学领域的研究与开发,为全球的科研机构、高校和企业提供高质量的生命科学产品和技术服务。公司拥有一支由资深科学家和技术专家组成的团队,具备丰富的行业经验和专业知识,能够为客户提供定制化的解决方案和全方位的技术支持。


Bio Academia公司的产品与服务包括:

(1)生命科学试剂:Bio Academia公司提供一系列生命科学试剂,包括但不限于DNA/RNA提取试剂、PCR试剂、酶类试剂、细胞培养试剂等。这些试剂均经过严格的质量控制,确保实验的准确性和可靠性。

(2)实验耗材与仪器:公司还销售各种实验耗材,如离心管、PCR管、培养皿等,以及生命科学研究中常用的仪器设备,如离心机、PCR仪、电泳仪等。这些耗材和仪器均来自知名品牌,质量有保障。

(3)技术服务:Bio Academia公司提供多种技术服务,如分子生物学实验设计、实验技术培训、数据分析等。公司的技术团队能够根据客户的具体需求,提供定制化的技术解决方案,帮助客户解决实验中遇到的问题。


Bio Academia公司的产品和服务广泛应用于生物学、医学、农学等多个领域。例如,在生物学研究中,公司提供的试剂和耗材可用于基因克隆、基因表达分析、蛋白质纯化等实验;在医学研究中,公司的产品和服务可用于疾病诊断、药物筛选等;在农学研究中,公司的产品和服务可用于作物遗传改良、病虫害防控等。

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艾美捷科技代理42 life sciences品牌全系列产品


42 life sciences是一家位于德国北部不来梅港的中小型企业。42 life sciences专注于开发和生产用于免疫组化(IHC)及原位杂交(ISH)应用的创新试剂。公司的核心优势在于拥有经验丰富的生物技术专家团队,确保产品开发高效聚焦,同时以可靠且具成本效益的方式进行生产。所有研发与制造流程均在我们自有设施中严格遵循EN ISO9001和EN ISO 13485标准执行。

42 life sciences公司的产品与服务包括:免疫组化与原位杂交创新试剂;外包生物缓冲液及试剂的生产业务。


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▎42 life sciences产品列表

分类品名产品描述货号规格
Chromogens for HRPAEC Solution IHC (ready-to-use)AEC (3-Amino-9-Ethylcarbazole) is a commonly used chromogen for immunohistochemical (IHC) procedures supplied in one liquid component.S-99012-100;S-99012-1000100ml;1000ml
Chromogens for HRPAEC Solution ISH (ready-to-use)AEC (3-Amino-9-Ethylcarbazole) is a commonly used chromogen for chromogenic in situ hybridization (CISH) procedures supplied in one liquid component.S-99010-500;S-99010-1000500ml;1000ml
Chromogens for HRPDAB Solution Set (2 components)DAB (3,3‘-diaminobenzidine) is a widely used chromogen in immunohistochemical and immunoblotting applications.S-99014-103;S-99014-1030103ml;1030ml
Chromogens for HRPHRP-Green Solution Set (2 components)The HRP-Green Solution Set is a new chromogen used in immunohistochemical and chromogenic in situ hybridization applications.S-99056-103;S-99056-1030103ml;1030ml
Chromogens for HRPHRP-Green Solution Set (MxE)The HRP-Green Solution Set (MxE) is a unique chromogen used in immunohistochemical and chromogenic in situ hybridization applications that is mixable in equal parts.S-99070-100;S-99070-2000100ml;2000ml
Chromogens for HRPAP-Red Solution Set IHC (2 components)The AP-Red Solution Set IHC is a chromogen used in immunohistochemical applications.S-99065-103103ml
Chromogens for HRPAP-Red Solution Set ISH (2 components)The AP-Red Solution Set ISH is a chromogen used in chromogenic in situ hybridization applications.S-99061-10301030ml
Chromogens for HRPNBT/BCIP Solution (ready-to-use)The NBT/BCIP Solution is a chromogen used in immunohistochemical and chromogenic in situ hybridization applications.S-99064-500500ml
CounterstainsMayer`s Hematoxylin Solution (ready-to-use)Mayer’s Hematoxylin Solution is a staining reagent for histological applications.S-99025-10001000ml
CounterstainsNuclear Blue Solution (ready-to-use)Nuclear Blue Solution is a hematoxylin based reagent for counterstaining applications in in situ hybridization (ISH) and immunohistochemistry (IHC) procedures using common chromogens like AEC and DAB.S-99035-10001000ml
CounterstainsNuclear Fast Red Solution (ready-to-use)Nuclear Fast Red Solution is designed for use as a counterstaining solution in immunohistochemistry (IHC) procedures using common chromogens like BCIP/NBT.S-99031-10001000ml
CounterstainsNuclear Red Solution (ready-to-use)Nuclear Red Solution is a nuclear fast red (a.k.a. Kernechtrot) based reagent for counterstaining applications in in situ hybridization (ISH) and immunohistochemistry (IHC) procedures.S-99033-500;S-99033-1000500ml;1000ml
CounterstainsNuclear Green Solution (ready-to-use)Ready-to-use Nuclear Green Solution optimized for the use in immunohistochemical (IHC) and in situ hybrididzation (ISH) procedures. Suitable for aqueous and non- aqueous mountants.S-99104-10001000ml
Ancillary Reagents1% BSA Ab Diluent (ready-to-use)The 1% BSA Ab Diluent is a stabilizer and diluent for all antibodies routinely used in immunohistochemistry (IHC) and in situ hybridization (ISH) applications.S-99068-10001000ml
Ancillary Reagentsone4all-Antibody Stabilizer (ready-to-use)The one4all-Antibody Stabilizer is a unique stabilizer for all antibody-enzyme conjugates routinely used in immunohistochemistry (IHC) and in situ hybridization (ISH) applications as well as in ELISA.S-99030-10001000ml
Ancillary ReagentsPepsin Solution (ready-to-use)Pepsin is a commonly used digestive enzyme for immunohistochemical (IHC) and in situ hybridization (ISH) procedures.S-99003-50;S-99003-500;S-99003-100050ml;500ml;1000ml
Ancillary ReagentsPepsin Solution for Cytology (ready-to-use)Pepsin Solution for Cytology is a digestive enzyme solution used in in situ hybridization (ISH) procedures in cytology specimens.S-99053-500;S-99053-1000500ml;1000ml
Ancillary ReagentsProteinase K Solution (ready-to-use)The Proteinase K Solution is specifically designed for use in the pretreatment of formalin-fixed tissue for in situ-hybridization (ISH) procedures.S-99080-100100ml
Ancillary ReagentsDuraTect™ DAPI/Antifade Solution (ready-to-use)The DuraTect™ DAPI/Antifade Solution is a refrigerator-stable formula for preserving fluorescence.S-99081-10;S-99081-100;S-99081-50010ml;100ml;500ml
Ancillary ReagentsDuraTect™ DAPI/Antifade Solution "ultra" (ready-to-use)The DuraTect™ DAPI/Antifade Solution "ultra" is a refrigerator-stable formula for preserving fluorescence.S-99098-5050ml
Ancillary ReagentsCOT-DNA, human (10mg/ml)The COT fraction of human genomic DNA predominantly consists of rapidly annealing repetitive sequences.S-99040-1;S-99040-10;S-99040-501mg;10mg;50mg



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艾美捷科技代理Screenfect品牌全系列产品


ScreenFect GmbH成立于2012年,是一家专注于细胞转染技术创新的德国生物技术公司。ScreenFect®转染试剂是该公司的核心产品,是依托组合化学方法构建独特化学文库,通过高通量细胞筛选平台高效开发的转染试剂。ScreenFect®转染试剂适用于多种核酸分子(包括pDNA、siRNA、mRNA、miRNA)的单转染与共转染,在难转染细胞(如原代细胞、干细胞)中具有优异性能。


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▎ScreenFect®转染试剂

● ScreenFect®A是一款通用型转染试剂,适用于pDNA、siRNA、mRNA的递送以及共转染实验,可广泛应用于多种细胞系(如HEK、HeLa、MEF)及部分原代细胞系。高效转染:在96孔板中仅需低于100ng DNA即可实现高转染效率。

● ScreenFect®siRN 是转染小干扰RNA双链体的理想选择,适用于HEK、HeLa、MEF等标准哺乳动物细胞系及多种原代细胞系。

● ScreenFect®mRNA是专为mRNA转染优化的高效试剂。

● ScreenFect®A-plus是一款多功能增强型转染试剂,适用于pDNA、siRNA、mRNA的转染及共转染实验,在几乎所有细胞系(包括难转染细胞)中均能实现高效转染。


货号品名规格Dilution buffer
S-3001ScreenFect®A1 mL50 mL
S-3001-2ScreenFect®A0,2 mL10 mL
S-4001ScreenFect®siRNA1 mL50 mL
S-4001-2ScreenFect®siRNA0,2 mL10 mL
S-5001ScreenFect®mRNA1 mL50 mL
S-5001-2ScreenFect®mRNA0,2 mL10 mL
S-6001ScreenFect®A-plus1 mL50 mL
S-6001-2ScreenFect®A-plus0,2 mL10 mL
S-2001-2ScreenFect Buffer10 mL-
S-2001ScreenFect Buffer50 mL-


ScreenFect®转染试剂具有以下特点:

● 低细胞毒性:显著降低对细胞活性的影响

● 省时一步法:支持细胞铺板与转染同步操作(即用型方案)

● 快速优化:针对新用户/新细胞系提供简易优化流程

● 血清兼容性:无需更换培养基,可直接在含血清环境下使用

● 无动物源成分:杜绝动物源性物质污染风险

● 高通量适用:完美适配大规模筛选实验需求


▎ScreenFect®UP-293

ScreenFect®UP-293 是一款专为高效生产抗体及蛋白设计的转染试剂,适用于HEK 293-F悬浮细胞体系。配合ScreenFect®Booster增效剂使用,可最大化提升悬浮细胞中的蛋白产量。


产品编号悬浮培养体积组分组分体积
S-8010-0.5L0.5 litreScreenFect®UP-2931 mL
ScreenFect®Booster2.5 mL
ScreenFect®Buffer35 mL
S-8010-1L1 litreScreenFect®UP-2932 mL
ScreenFect®Booster5 mL
ScreenFect®Buffer70 mL
S-8010-10L10 litresScreenFect®UP-29320 mL
ScreenFect®Booster50 mL
ScreenFect®Buffer700 mL
S-8010-50L50 litresScreenFect®UP-293100 mL
ScreenFect®Booster250 mL
ScreenFect®Buffer3.5 L
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▎ScreenFect®Booster

在完成HEK293F悬浮细胞的ScreenFect®UP-293转染后,于转染后16小时添加ScreenFect®Booster增效剂,可显著提升蛋白产量。该增效剂含特定复合组分,通过重编程细胞代谢路径(从增殖模式转向蛋白合成模式),从而高效提升大多数目标蛋白的表达水平。


货号品名规格
S-2001-2ScreenFect Buffer10 mL
S-2001ScreenFect Buffer50 mL


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